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HIV/AIDS Pathogenesis

Researchers report details of new studies and findings in the area of HIV/AIDS pathogenesis

Published in AIDS Weekly, November 14th, 2005

HIV/AIDS pathogenesis data are the focus of recent research from the United States.

Study 1: A significant proportion of very early nonsynonymous HIV mutations are selected by cytotoxic T lymphocytes.

According to recent research from the United States, "The full protein coding region of human immunodeficiency virus (HIV) genomes were sequenced using plasma collected from nine African-Americans prior to seroconversion and 7 to 28 days later. HIV mutations emerged in seven of these subjects at a genomewide rate of 2% per year."

"The location of nonsynonymous (NS) HIV mutations within these subjects was compared to their potential...

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