HIV/AIDS Exposure
CD91 expression increased on monocytes of exposed yet HIV-1-seronegative persons
Published in AIDS Weekly, November 14th, 2005
"The significantly higher surface expression of the surface heat-shock protein receptor CD91 on monocytes of human immunodeficiency virus type-1 (HIV-1)-infected, long-term nonprogressors suggests that HIV-1 antigen uptake and cross-presentation mediated by CD91 may contribute to host anti-HIV-1 defenses and play a role in protection against HIV-1 infection.
"To investigate this further, we performed phenotypic analysis to compare CD91 surface expression on CD14+ monocytes derived from a cohort of HIV-1-exposed seronegative (ESN) subjects, their seropositive (SP)...
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Source: AIDS Weekly (2005-11-14)
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