Immunodeficiency
Natural killer cell-mediated cytotoxicity spawns liver failure
Published in AIDS Weekly, November 14th, 2005
"NK cells represent the first line of defense against viral infections but, in the case of hepatitis B virus (HBV), may also be involved in liver injury. We here compared NK-cell activity of 11 patients with acute HBV infection, either human immunodeficiency virus (HIV)-positive or HIV-negative, with that of 11 healthy subjects," scientists in Italy report.
"One of the HIV-positive patients, characterized by a severe immunodeficiency, died 3 weeks after hospitalization for HBV-related fulminant hepatitis (FH). He displayed a remarkable NK-cell cytotoxicity against both cell lines...
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Source: AIDS Weekly (2005-11-14)
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