Published in AIDS Weekly, November 21st, 2005
Study 1: There is a high HIV-1 RT sequence conservation under drug pressure despite continuous appearance of mutations.
In a recent article published in the Journal of Virology, scientists in Italy conducted a study "to define the extent of sequence conservation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) in vivo, the first 320 amino acids of RT obtained from 2,236 plasma-derived samples from a well-defined cohort of 1,704 HIV-1-infected individuals (457 drug naive and 1,247 drug treated) were analyzed and examined in...
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