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HIV/AIDS Vaccines Development

Studies add new findings to HIV/AIDS vaccines development body of knowledge

Published in AIDS Weekly, November 21st, 2005

New findings from the United States and Japan describe advances in HIV/AIDS vaccines development.

Study 1: Researchers evaluate the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1 in a recent issue of the Journal of Virology.

"The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) complex comprises three gp120 exterior glycoproteins each noncovalently linked to a gp41 transmembrane glycoprotein. Monomeric gp120 proteins can elicit antibodies capable of neutralizing atypically sensitive test viruses in vitro, but these antibodies...

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