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HIV/AIDS Vaccine

Mucosal and systemic immunity involved in male genital tract secretions

Published in AIDS Weekly, November 21st, 2005

Both mucosal and systemic immune compartments contribute to the humoral immunity in human male genital tract secretions.

According to a study from the United States, "In contrast to numerous studies of female genital tract secretions, the molecular properties of antibodies and the magnitude of humoral responses in human male genital tract secretions to naturally occurring antigens and to mucosal and systemic immunizations have not been extensively investigated. Therefore, seminal plasma (SP) collected from healthy individuals was analyzed with respect to Ig levels, their isotypes, molecular forms of IgA, and for the presence of antibodies to naturally occurring...

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