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HIV/AIDS Therapy

Switching from a protease inhibitor to nevirapine maintains viral control

Published in AIDS Weekly, November 28th, 2005

Switching from a protease inhibitor to nevirapine maintains viral control.

In a recent study, researchers in Spain conducted a study to "assess the antiviral efficacy and safety of switching from a protease inhibitor (PI) to nevirapine in patients with long-term HIV-1 RNA suppression on PI-containing regimens, and to assess its influence in the adherence to treatment."

"In an open-label multicenter study, 160 HIV-infected patients with undetectable viral load for at least 6 months on a PI-containing regimen were randomized to either continue with their PI regimen (n=79) or replace PI with nevirapine (n=8 1).

"Clinical assessment...

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