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HIV/AIDS Pathogenesis

New findings in the area of HIV/AIDS pathogenesis detailed

Published in AIDS Weekly, December 5th, 2005

Data on HIV/AIDS pathogenesis are outlined in reports from France and the United States.

Study 1: HIV-1 variants from single plasma samples have various neutralization sensitivities.

According to recent research from France, "Individuals infected with human immunodeficiency virus type 1 (HIV-1) harbor a mixture of viral variants with different sequences and in some instances with different phenotypic properties.

"Major and rapid fluctuations in the proportion of viral variants coexisting in an infected individual can be observed under strong pharmacological and immune selective pressure."

"Because of the short...

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