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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . December 19th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS HAART - Initial therapy has diminished efficacy in patients with low CD4 counts and high viral loads

HIV/AIDS Neurotoxicity - Aciclovir protects against quinolinic acid-induced oxidative neurotoxicity

HIV/AIDS-Associated Pulmonary Hypertension - Secreted HIV gp120 proteins induce lung endothelial cell injury

Preventive Medicine - Safe male circumcision procedure offered in developing countries to decrease STD incidence

Bioethics - Controversies and interests drive 'Bioethics in action'

Cerebral Toxoplasmosis - PCR plus high titers of anti-Toxoplasma gondii IgG antibodies diagnose cerebral toxoplasmosis

Clinical Trials - Irish pharmaceutical company reports launch of reverse transcriptase phase III trials

Collaborations - Biopharma company signs agreement with Xinhua Finance to help open Asian marketplace

Collaborations - Diagnostics test company enters joint venture with Chinese firm and northern China hospital

Diagnostics - Diagnostic tests provider engages Partner International to strengthen European distribution network

HIV/AIDS Pathogenesis - Recent findings in HIV/AIDS pathogenesis provide new insights

Diagnostics - Integrating multiantigen ELISA with AFB smear improves sensitivity for active TB screening

Disease Control - Public awareness campaign resulted in community involvement in syphilis control efforts

Drug Development - Agreement signed to develop process, manufacture AIDS vaccine candidate for trials

Drug Development - Aptivus sustains convincing anti-HIV effect through 48 weeks

Drug Development - Pharma company to license novel drug target for HIV treatment

Drug Development - Study reported 7% of HIV-1+ patients who switched treatment regimens experienced viral rebound

HIV/AIDS Pathogenesis - Researchers report details of new studies and findings in the area of HIV/AIDS pathogenesis

Drug Resistance - Linezolid is effective for the treatment of multidrug-resistant tuberculosis

Drug Resistance - Resistance to antituberculosis drugs increasing in Botswana

Gonorrhea - Antibiotic resistance in Neisseria gonorrhoeae renders gonorrhea untreatable

HIV/AIDS Behavioral Medicine - Crystal methamphetamine and ecstasy differ in relation to unsafe sex among young gay men

HIV/AIDS Coinfection - HHV8 enhances HIV replication in acutely infected cells and induces reactivation

HIV/AIDS Diagnostics - Results demonstrate importance of reagent selection for monitoring of HIV responses

HIV/AIDS Diet & Nutrition - AIDS-related active opportunistic infections associated with nutritional status

HIV/AIDS Drug Adherence - Nurse-delivered adherence intervention improves knowledge and HAART adherence

HIV/AIDS Drug Development - P1 chain-extended HIV protease inhibitors active against drug-resistant mutants

HIV/AIDS Drug Interactions - Few data are available regarding PI interactions with other complex treatment regimens

HIV/AIDS Drug Resistance - Reports describe recent advances in HIV/AIDS drug resistance research

HIV/AIDS Epidemiology - HIV prevalence increasing among injecting drug users in England and Wales

HIV/AIDS HAART - Atazanavir-treated patients have better lipid profile than lopinovir/ritonavir-treated patients

HIV/AIDS HAART - Combination therapy is more effective in NRTI-experienced children than NFV/NVP/d4T

HIV/AIDS HAART - HAART reduced the rate of progression from AIDS to HIV infection with end-stage renal disease

HIV/AIDS HAART - Polymorphisms of Fas and Fas ligand influence immunoreconstitution triggered by HAART

HIV/AIDS HAART Complications - Neurologic complications from HAART can lead to decreased drug adherence

HIV/AIDS HAART Resistance - Rate of antiretroviral resistance similar among intravenous drug users and nondrug users

HIV/AIDS Occupational Exposure - Probably of HIV transmission with accidental exposure in a surgical setting is low

HIV/AIDS Pathogenesis - Findings in HIV/AIDS pathogenesis provide new insights

HIV/AIDS Pathogenesis - Sam68 may play a role in the immune function of lymphocytes in HIV infection

HIV/AIDS Pharmacology - Pharmacokinetic properties of NRTIs determine appropriateness for once daily dosing

HIV/AIDS Prevention - Phase II trial initiated in South Africa to test HIV vaccine candidate

HIV/AIDS Research - Behavioral study shows patients willing to consider self-injectable therapy

HIV/AIDS Research - Clinical trial shows MK-0518 tablet has potent reduction in viral load as monotherapy

HIV/AIDS Research - HIV/AIDS research shows new drugs offer alternatives for individualized care

HIV/AIDS Research - Kaletra combination therapy shown to maintain undetectable viral load in HIV patients

HIV/AIDS Research - New European HIV treatment guidelines recommend boosted Invirase as first choice protease inhibitor

HIV/AIDS Risk Behavior - Alcohol abuse is common among HIV-infected subjects in St. Petersburg

HIV/AIDS Therapy - Antiretroviral therapy interruption during chronic HIV-1 infection is not beneficial

HIV/AIDS Therapy - DOTS principles adapted to deliver antiretroviral therapy in Malawi

HIV/AIDS Therapy - U.S. FDA approves updated labeling for LEXIVA

HIV/AIDS Vaccine Development - Envelope vaccines derived from South African subtype C HIV-1 TV1 strain have been evaluated

HIV/AIDS Vaccine Development - Semliki Forest virus particles efficiently expand HIV-1-specific T cell responses

HIV/AIDS-Related Infection - Cervicovaginal secretions contribute to resistance to herpes simplex infection in HIV/AIDS

HIV/AIDS-Related Seizures - Aggressive seizure managements limits the risk of status epilepticus in HIV/AIDS

Hepatitis C Virus - Neuropsychological impairment is a risk in HIV- and HCV-infected women

Herpesvirus - HHV-8 is not associated with the pathogenesis of gastrointestinal stromal tumors

Invasive Fungal Infections - DNA microarray detects and identifies fungal pathogens involved in invasive mycoses

Medicaid - Texas Medicaid begins covering HIV resistance testing

Menopause - HIV infection and immunosuppression are associated with earlier menopause onset

Mergers & Acquisitions - Maxim Biomedical, Inc. acquires diagnostic test business

Osteoporosis - Postmenopausal HIV-positive women are at much higher risk for osteoporosis

Personnel - Dr. Robert Bast joins scientific advisory board of Xolair developer

Personnel - Keith Gregg and Paul Hopper join board of antibody-based treatment developer

Pneumococcal Vaccine - Microbes may modulate antibody response to glucuronoxylomannan in AIDS

Pneumococcal Vaccine - Past polysaccharide vaccine did not affect pneumococcal vaccine response in HIV-infected Ugandans

Professional Education - Healthcare providers in Canada unaware of actual transmissibility of HIV and chlamydia

Public Health - Web-based reporting systems to evaluate health promotion are well accepted

Vaccine Research - New gene chip could ehance scientists' ability to develop vaccines

Virology - Aurintricarboxylic acid may be a potent antiviral drug

Virology - Reports advance knowledge in virology research

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