HIV/AIDS Neurotoxicity
Aciclovir protects against quinolinic acid-induced oxidative neurotoxicity
Published in AIDS Weekly, December 19th, 2005
According to a study from South Africa, "AIDS-related encephalopathy, including AIDS dementia complex (ADC) and the opportunistic disease, herpes simplex encephalitis (HSE), are postulated to arise due to the release of neurotoxic products, such as quinolinic acid (QUIN), by activated microglial cells in the brain."
"QUIN causes a cascade of events to occur, which leads to the production of reactive oxygen species (ROS), these being ultimately responsible for oxidative neurotoxicity. The antiherpes antiviral aciclovir has been reported to protect against neuron loss in HSE,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2005-12-19)
More Articles from AIDS Weekly
- HIV/AIDS HAART
Initial therapy has diminished efficacy in patients with low CD4 counts and high viral loads - HIV/AIDS-Associated Pulmonary Hypertension
Secreted HIV gp120 proteins induce lung endothelial cell injury - Preventive Medicine
Safe male circumcision procedure offered in developing countries to decrease STD incidence - Bioethics
Controversies and interests drive 'Bioethics in action' - Cerebral Toxoplasmosis
PCR plus high titers of anti-Toxoplasma gondii IgG antibodies diagnose cerebral toxoplasmosis - Clinical Trials
Irish pharmaceutical company reports launch of reverse transcriptase phase III trials - More from this issue of AIDS Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
