HIV/AIDS Therapy
Antiretroviral therapy interruption during chronic HIV-1 infection is not beneficial
Published in AIDS Weekly, December 19th, 2005
According to a study from England, "Increasing numbers of patients are choosing to interrupt highly active antiretroviral therapy (HAART). We describe the effect of patient-directed treatment interruption (PDTI) on plasma viral loads (pVL), proviral DNA (pDNA), lymphocyte subsets, and immune responses in 24 chronically HIV-1 infected individuals."
"Patients were divided into group A with pVL>50 copies/mL and group B with pVL <50 copies/mL, prior to the PDTI. pVL rose significantly in group B during the first month off HAART and was associated...
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Source: AIDS Weekly (2005-12-19)
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