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HIV/AIDS Pathogenesis

Research add new data to HIV/AIDS Pathogenesis body of knowledge

Published in AIDS Weekly, January 16th, 2006

New findings from Japan and the United States describe advances in HIV/AIDS Pathogenesis.

Study 1: HIV-1-specific cytotoxic T lymphocytes produce a single cytokine after stimulation with HIV-1-infected CD4 cells.

According to a study from Japan, "Although human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells can produce various cytokines that suppress HIV-1 replication or modulate anti-HIV-1 immunity, the extent to which HIV-1-specific CD8+ T cells produce cytokines when they recognize HIV-1-infected CD4+ T cells in vivo still remains unclear.

"We first analyzed the abilities of 10 cytotoxic T-lymphocyte (CTL) clones...

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