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HIV/AIDS HAART

Genetically distinct HIV-1 quasispecies persist during prolonged HAART

Published in AIDS Weekly, January 16th, 2006

Genetically distinct HIV-1 quasispecies persist in monocytes and CD4 T cells during prolonged HAART.

According to recent research published in the journal AIDS, "Reservoirs of HIV-1 are a major obstacle to virus eradication. There is therefore a need to clearly understand the molecular nature of the virus populations that persist in patients with sustained suppression of plasma viremia on highly active antiretroviral therapy (HAART)."

"We performed a detailed analysis of the genotypes of HIV-1 quasispecies isolated from highly purified blood cell types taken from three selected patients with sustained undetectable viral loads on HAART for 7...

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