AIDS Weekly

Drug Development - Indirubin-3'-monoxime inhibits P-TEFb function and HIV-1 replication

HIV/AIDS Drug Delivery - Zidovudine plasma levels increase when dosed as a prodrug in liposomal form

HIV/AIDS Drug Resistance - Drug-resistance mutations identified in HAART-naive HIV-infected patients

HIV/AIDS Therapy - Dextrin sulphate against HIV is well tolerated without systemic absorption

HIV/AIDS Vertical Transmission - Lower vertical HIV-1 transmission in boys independent of type of delivery or prophylaxis

Allergy & Immunology - Intracisternal A-type retroviral particle type I isolated from SLE patients

Avian Influenza - Diagnostics company begins work on rapid test kit for avian influenza

Blood Safety - Pharma company submits CE Mark application for Intercept Blood System for plasma in Europe

Cervical Screening - Racial differences exist in attitudes towards cervical screening in HIV-positive women

Clinical Trials - Durable efficacy of enfuvirtide plus optimized background of retrovirals demonstrated over 48 weeks

Clinical Trials - Phase 3 trial of recombinant human growth hormone for HIV-associated HARS meets endpoints

DNA Research - HIV-1 env-based NASBA molecular beacon assay discriminates between subcluster C and C'

Disease Associations - Hepatitis C virus RNA level is a predictor of end stage liver disease death

Drug Development - Chemical in sunflowers stops HIV from reproducing in lab cultures

Drug Safety - LPV/RTV further increases total and HDL cholesterol without affecting total/HDL ratio

Efavirenz - Efavirenz treatment causes neurological symptoms distinct from depression and anxiety

Epidemiology - Sexual network structure affects epidemic thresholds

Funding - U.S. government awards over $56 million to eliminate health disparities

HIV/AIDS Adverse Drug Reaction - HIV entry inhibitor TAK-779 attenuates atherogenesis in LDL receptor deficiency

HIV/AIDS Antimicrobials - Mannose-binding lectin modulates cytokine response and HIV replication

HIV/AIDS Behavioral Medicine - HIV-specific social support predicts less sexual risk behavior in gay male couples

HIV/AIDS Behavioral Medicine - High-risk sex with uninfected partners prevalent in patients with drug-resistant viremia

HIV/AIDS Diagnostics - Brief screening tool targets substance abuse and mental illness in HIV/AIDS

HIV/AIDS Discrimination - HIV/AIDS patients in Mumbai experience discrimination in healthcare settings

HIV/AIDS Drug Delivery - Subcutaneous IL-2 positively impacts long-term quality of life in HIV/AIDS

HIV/AIDS Drug Development - Broad-spectrum nonnucleoside reverse transcriptase inhibitors have antiviral activity

HIV/AIDS Genetics & Genomics - CYP2B6 genetic variability determined for populations of African and Asian origin

HIV/AIDS Genetics & Genomics - Novel HIV-1 circulating AIDG intersubtype recombinant form is identified in Cuba

HIV/AIDS HAART - Boosted indinavir plus efavirenz yields durable response in patients failing NRTI regimens

HIV/AIDS HAART - HAART efficacy and toxicity widely variable between HIV-infected patients

HIV/AIDS HAART - HAART promotes salivary microbiota in HIV-positive women

HIV/AIDS HAART - PI ability to impair glucose disposal correlates with degree of insulin resistance

HIV/AIDS HAART - Researchers' findings advance HIV/AIDS HAART research

HIV/AIDS Healthcare - Nurse practitioners and physician assistants provide high quality HIV care

HIV/AIDS Hypercholesterolemia - Risk factors identified for hypercholesterolemia risk at HAART initiation

HIV/AIDS Opportunistic Infection - Withdrawal of PCP prophylaxis after immune reconstitution safe in pediatric HIV/AIDS

HIV/AIDS Pathogenesis - Hsp40 necessary for HIV-1 Nef-mediated enhancement of viral gene expression and replication

HIV/AIDS Pathogenesis - IL-7R alpha loss associated with CD4 T-cell depletion and high IL-7 in HIV/AIDS

HIV/AIDS Pathogenesis - New findings in the area of HIV/AIDS pathogenesis described

HIV/AIDS Pathogenesis - Recent findings in HIV/AIDS pathogenesis provide new insights

HIV/AIDS Pathogenesis - Studies describe new findings in HIV/AIDS pathogenesis research