HIV/AIDS Antimicrobials
Mannose-binding lectin modulates cytokine response and HIV replication
Published in AIDS Weekly, January 30th, 2006
According to a recently published report from Norway, "Mannose-binding lectin (MBL) is a soluble receptor of the innate immune system, probably contributing to antimicrobial defense.
"The possible role of MBL in HIV infection is unclear. Peripheral blood mononuclear cells (PBMCs) from 28 HIV-infected patients and 13 healthy controls were stimulated with MBL and costimulated with HIV-1 gp120 or mannan from Saccharomyces cerevisiae before inflammatory responses in PBMC cultures were examined by enzyme-linked immunosorbent assay (ELISA) and flow cytometry."
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Source: AIDS Weekly (2006-01-30)
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