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HIV/AIDS Opportunistic Infection

Withdrawal of PCP prophylaxis after immune reconstitution safe in pediatric HIV/AIDS

Published in AIDS Weekly, January 30th, 2006

Withdrawal of Pneumocystis jirovecii pneumonia prophylaxis after immune reconstitution is safe in pediatric HIV/AIDS.

"In HIV-infected adults Pneumocystis jirovecii pneumonia (PCP) prophylaxis can be safely withdrawn after immune reconstitution due to the introduction of highly active antiretroviral therapy (HAART). With regard to children only a small amount of data has been published.

"The present study investigated whether the withdrawal of PCP prophylaxis after immune reconstitution is safe in HIV-infected children. A retrospective analysis at 10 European centers belonging to the Pediatric European Network on the treatment of AIDS...

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