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HIV/AIDS Therapy

Dextrin sulphate against HIV is well tolerated without systemic absorption

Published in AIDS Weekly, January 30th, 2006

Early study results show dextrin sulphate is well tolerated without systemic absorption.

Scientists writing in the journal Sexually Transmitted Diseases reported, "This phase I dose-ranging study of 2 weeks of twice-daily dextrin sulphate (DS), a sulphated polymer with in vitro activity against HIV, was designed in 2 parts. Part A was a randomized, placebo-controlled, double-blind, 3-arm trial (DS4%, DS1%, placebo) in HIV-negative women."

"In part B," described S. McCormack and colleagues, "HIV-positive women received DS4% and HIV-negative women were randomized to DS4% or no gel. One hundred women were enrolled from 2 sites (London and...

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