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Allergy & Immunology

Intracisternal A-type retroviral particle type I isolated from SLE patients

Published in AIDS Weekly, January 30th, 2006

Intracisternal A-type retroviral particle type I has been isolated from systemic lupus erythematosus patients.

"Prior studies have linked retroviruses to various arthropathies and autoimmune diseases. Sjogren's syndrome (SS), a systemic autoimmune disease, is characterized by aggressive infiltration of lymphocytes into the salivary and lacrimal glands, resulting in destruction of the glands and dry mouth and eyes (sicca syndrome).

"The infiltrating lymphocytes in SS may become overtly malignant, and thus, the incidence of lymphoma is greatly increased in SS patients," scientists in the United States report.

According to the...

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