AIDS Weekly

HIV/AIDS Drug Development - Bifunctional HIV-1 inhibitors simultaneously block CD4 and CCR5 receptors

HIV/AIDS Drug Interaction - Ritonavir increases systemic exposure of prednisolone

HIV/AIDS Drug Resistance - Recent HIV-1 seroconverters more likely to have transmitted drug resistance

HIV/AIDS Epidemiology - Frequency of HIV/AIDS protective SDF1-3'A gene high among blood donors in Crete

HIV/AIDS HAART - HIV RNA sustained below 20 copies/mL may prevent 184V mutation in CD4 cell DNA

Allergy & Immunology - Cytomegalovirus infection inhibits immune responses generated against P. carinii

Antibacterial Agents - Retroscreen study shows chlorhexidine hand sanitizer over 99% effective on bird flu virus

Cervical Cancer - HIV infection associated with increased risk of cervical cancer precursor

Clinical Trials - Marketing application for investigational HIV protease inhibitor filed in Europe

Clinical Trials - Peg-Intron maintenance study in patients coinfected with hepatitis C and HIV initiated

DNA Vaccine - CD4+ T cell-independent DNA vaccine shows promise against opportunistic infections

Diagnostics - Biomedical company submits Aware OMT test to Chinese SFDA

Genetics & Genomics - IGS sequence analyses delineates C. neoformans and C. gattii at genotypic levels

HIV Detection - HIV type 1 DNA sequence can be detected using plasmonics nanoprobes

HIV Therapy - HIV integrase inhibitor GS 9137 advances to phase II clinical trial

HIV-2 Pathogenesis - HIV-2 has more open and accessible V3 domain than HIV-1 due to glycan packing differences

HIV/AIDS Adverse Drug Reaction - mtDNA or lactate/pyruvate ratio poor markers of NRTI-associated mitochondrial toxicity

HIV/AIDS Behavioral Medicine - Condom use among youth varies according to whether partner is casual or steady

HIV/AIDS Behavioral Medicine - Men who pay women for sex have higher rates of STIs and low HIV testing levels

HIV/AIDS Behavioral Medicine - Optimistic HIV/AIDS perception leads to unprotected sex among men who have sex with men

HIV/AIDS Behavioral Medicine - Seasonal work migration and unsafe sex practices facilitate HIV spread in China

HIV/AIDS Diagnostics - Cobas Amplicor HIV-1 Monitor 1.5 and Versant HIV-1 RNA 3.0 assays compared

HIV/AIDS Diagnostics - Diagnostics company receives initial European order for instant rapid HIV tests

HIV/AIDS Diagnostics - Indeterminate rates for HIV genotyping are higher with LiPA compared with sequencing tests

HIV/AIDS Drug Adherence - Pharmacist consultation educates HIV/AIDS patients and improves HAART adherence

HIV/AIDS Drug Adherence - Risk factors for HAART nonadherence in Brazil determined

HIV/AIDS Drug Resistance - Different HAART resistance patterns occur in responders and nonresponders

HIV/AIDS Drug Resistance - Enfuvirtide genotypic and phenotypic resistance rapidly disappears after discontinuation

HIV/AIDS Drug Resistance - HIV-1 drug resistance mutations increasing in Thailand

HIV/AIDS Drug Resistance - Previously unreported HIV-1 RT mutations associated with NRTI/NNRTI phenotypic resistance

HIV/AIDS Epidemiology - Determination of gag and env subtypes of HIV-1 detected among injecting drug users

HIV/AIDS Epidemiology - Different patient population accounts for increased AIDS incidence in France

HIV/AIDS Epidemiology - HIV-1 infection risk associated with SDF1 polymorphism and CXCR4 variation in South Africa

HIV/AIDS Epidemiology - HIV-1 subtype C is the predominant strain in southern Brazil

HIV/AIDS Epidemiology - Perinatal HIV transmission rate decreased in Sao Paulo

HIV/AIDS Fitness & Wellness - Increased trunk/limb fat ratio associated with adverse metabolic parameters after HAART

HIV/AIDS Genetics & Genomics - Genetic variation pattern at CCR5-Delta 32 consistent with neutral evolution

HIV/AIDS HAART - Archived resistant HIV linked to sequences before HAART interruption

HIV/AIDS HAART - GNB3 C825T polymorphism associated with short-term success of HAART treatment

HIV/AIDS HAART - HDL and LDL cholesterol levels increase in children on HAART

HIV/AIDS HAART - Tenofovir DF salvage therapy well-tolerated and effective in pediatric HIV/AIDS

HIV/AIDS HAART - Viral load response to HAART independently predicts new AIDS event in late stage AIDS

HIV/AIDS HAART Failure - HAART interruption and resistance mutation emergence causes virological failure

HIV/AIDS Orphans - HIV positivity or losing a parent to AIDS increases institutionalization in Brazil

HIV/AIDS Pathogenesis - Exogenous IL-7 may be of benefit during pathogenic SIVmac and HIV infection

HIV/AIDS Pathogenesis - Findings in HIV/AIDS pathogenesis provide new insights

HIV/AIDS Pathogenesis - New findings in the area of HIV/AIDS pathogenesis detailed