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HIV/AIDS Drug Resistance

Recent HIV-1 seroconverters more likely to have transmitted drug resistance

Published in AIDS Weekly, February 6th, 2006

Recent HIV-1 seroconverters are more likely to have transmitted drug resistance.

In a recently published report, investigators in England conducted a study to "examine factors influencing the rate of transmitted drug resistance (TDR) among seroconverters, with particular emphasis on 3 widely used genotypic drug resistance algorithms.

"The study used data from CASCADE (Concerted Action on seroconversion to AIDS and Death in Europe), a collaboration of seroconverter cohorts in Europe and Canada. Genotypic resistance data were derived within 18 months of the last seronegative test or date of laboratory evidence of acute infection and before the...

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