HIV/AIDS Pathogenesis
New findings in the area of HIV/AIDS pathogenesis detailed
Published in AIDS Weekly, February 6th, 2006
Study 1: Histone deacetylase 6 regulates HIV-1 infection.
"Efficient human immunodeficiency virus (HIV)-1 infection depends on multiple interactions between the viral gp41/gp120 envelope (Env) proteins and cell surface receptors. However, cytoskeleton-associated proteins that modify membrane dynamics may also regulate the formation of the HIV-mediated fusion pore and hence viral infection," scientists in Spain report.
"Because the effects of HDAC6-tubulin deacetylase on cortical alpha-tubulin regulate cell migration and immune synapse organization," the...
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Source: AIDS Weekly (2006-02-06)
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