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HIV/AIDS Blood Safety

Cobas Ampliscreen HIV-1 test detected blood donor seroconversion from minipool

Published in AIDS Weekly, February 13th, 2006

The Cobas Ampliscreen HIV-1 test detected a blood donor seroconversion from a minipool of 16 patient specimens.

"The introduction of nucleic acid amplification technology (NAT) for screening pooled or individual donations remarkably improved the safety of blood products. The size of minipooled NAT is considered critical for identification of HIV-1 infected donors during preseroconversion phase of infection," scientists in Italy report.

According to the authors, "We describe a case of HIV-1 infection in a serologically negative repeat blood donor identified by 16 minipool (MP) NAT. The donation was tested by Roche Cobas AmpliScreen HIV-1 Test with...

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