HIV/AIDS HAART
HIV-1 K103N mutation after HAART withdrawal has little impact on viral fitness
Published in AIDS Weekly, February 27th, 2006
According to recently published research from Italy, "To investigate the dynamics of the K103N mutation following the withdrawal of non-nucleoside reverse transcriptase inhibitors (NNRTIs), we selected the HIV-infected patients with the mutation at the time or after the failure of an NNRTI-containing regimen from an observational database.
"Of 62 patients fulfilling the inclusion criteria, 39 continued antiretroviral treatment without NNRTIs (group A), whereas 23 discontinued all antiretrovirals after NNRTI failure (group B). A total of 149 tests were analyzed, with a...
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Source: AIDS Weekly (2006-02-27)
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