HIV/AIDS Drug Development
Lamivudine and siRNA-M184V inhibits replication of wild-type and variant M184V HIV
Published in AIDS Weekly, March 13th, 2006
According to a study from Germany, "RNA interference is a powerful tool used to inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro. Almost all HIV-1 genes have been targets for small interfering RNA (siRNA) molecules, and HIV-1 replication can be specifically and successfully inhibited by this technique."
"RNA interference has been proposed as an alternative strategy to inhibit replication of drug-resistant viruses that emerge during suboptimal antiretroviral therapy for HIV-1.
"To investigate...
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Source: AIDS Weekly (2006-03-13)
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