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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . March 20th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Diagnostics - Genotypic and phenotypic clinical cut-off levels determined for ritonavir-boosted saquinavir

HIV/AIDS Drug Resistance - Infant-only prophylaxis eliminates nevirapine resistance development in mothers and infants

HIV/AIDS Pharmacokinetics - Interpatient variability in plasma efavirenz levels determined by gender and race

HIV/AIDS Transmission - Cell reservoirs in lymph nodes infected with HIV-1 subtype E differ from subtype B

Pediatrics HIV/AIDS Risk Factors - Infants perinatally infected with HIV at risk from BCG vaccination

Business Update - Blood safety scientific advisory board established by Cerus

Candida - U.S. FDA approves new treatment for fungal infections

Diagnostics - MedMira signs Clindia Benelux as Netherlands distributor for instant HIV test

Diagnostics - Mixed Mycobacterium lentiflavum and M. avium infections detected by genotyping

Drug Development - Bristol-Myers Squibb seeks to expand access to HIV/AIDS medicine

Drug Development - HIV-1 fusion inhibitors moderately inhibit fusion of SARS-CoV with target cells

Feline Immunodeficiency Syndrome - Low-dose interferon-alpha treatment prolongs survival in FIV infection

Finance - Monogram announces revenue of $12.7 million for the fourth quarter

Finance - Panacos reports net loss of $8.3 million or $0.17 per share

Foamy Virus Infection - Foamy virus RNA quantified in tissues of healthy and SIV-infected macaques

HIV/AIDS Adverse Drug Reactions - Adverse events are most common reasons for generic HAART modification in Southern India

HIV/AIDS Behavioral Medicine - Drug relief hospital-based AIDS education improves prevention behaviors

HIV/AIDS Behavioral Medicine - Safe sex interventions have had a positive impact on female sex workers in Pune

HIV/AIDS Dementia - Depression and neurocognitive performance over time related to various HIV-related factors

HIV/AIDS Diagnostics - HIV infection probability in a child depends on nature/number of manifestations present

HIV/AIDS Diagnostics - HPLC-MS/MS simultaneously quantifies seven protease inhibitors in plasma

HIV/AIDS Diagnostics - Ordering patterns for HIV resistance tests differ significantly among clinicians

HIV/AIDS Diagnostics - Setema appointed by Chembio to distribute its rapid HIV tests in Ethiopia

HIV/AIDS Diagnostics - Simple and accurate diagnostic tools monitor HIV infection

HIV/AIDS Disease Control - AIDS epidemic fueled by injection drug use in China

HIV/AIDS Drug Abuse - Illness burden mediates relationship between pain and illicit drug use in HIV/AIDS

HIV/AIDS Drug Development - Findings describe new data in HIV/AIDS drug development research

HIV/AIDS Drug Interaction - Lopinavir/ritonavir and valproic acid interaction may exacerbate bipolar disorder

HIV/AIDS Epidemiology - New findings in HIV/AIDS epidemiology described

HIV/AIDS HAART - Calculations of creatinine clearance and anion-gap related to tenofovir therapy are minor

HIV/AIDS HAART - New findings in the area of HIV/AIDS HAART described

HIV/AIDS HAART - New findings in the area of HIV/AIDS HAART detailed

HIV/AIDS HAART - Poor HAART adherence and an increased drug resistant HIV-1 strain in China related

HIV/AIDS Molecular Structure - Rous sarcoma virus virions contain fewer copies of Gag than HIV-1

HIV/AIDS Pathogenesis - CTL targeting of HIV-1 is similar in identical twins 20 years after neonatal infection

HIV/AIDS Pathogenesis - HIV Vpr fuels the progression of AIDS

HIV/AIDS Pathogenesis - HIV-1 Tat represses bone morphogenetic protein receptor-2 transcription in macrophages

HIV/AIDS Pathogenesis - HIV-1 V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations

HIV/AIDS Pathogenesis - HIV-1 Vpr induces ATR activation by targeting host cell DNA

HIV/AIDS Pathogenesis - HIV-1 viral auxiliary proteins have significant impact on HIV infection outcome

HIV/AIDS Pathogenesis - Increased IL-7 correlates with decreased CD127 and increased CD132 expression in HIV/AIDS

HIV/AIDS Pathogenesis - Uracil DNA glycosylase is dispensable for HIV-1 replication

HIV/AIDS Prognosis - Despite moderate HIV viremia, clinical progression risk is low

HIV/AIDS Research - Monogram and Merck collaborate on phase III trials of HIV-1 integrase inhibitor

HIV/AIDS Research - Progenics Pharmaceuticals HIV drug, PRO 140, receives U.S. FDA fast-track designation

HIV/AIDS Research - Tanox research reaffirms tropism independence of TNX-355 for HIV

HIV/AIDS Risk Factors - Environmental and economic factors that increase risk of HIV/AIDS outlined in new book

HIV/AIDS Risk Factors - Having an HIV+ sex partner independently associated with time to HIV seroconversion

HIV/AIDS Risk Factors - Women in Cambodia at increased risk of HIV infection from husbands

HIV/AIDS Testing - Chembio's rapid HIV test selected by Nigeria

HIV/AIDS Therapy - HIV/malaria therapies given concurrently during pregnancy may prove incompatible

HIV/AIDS Therapy - Medivir designates a clinical candidate drug for HIV/AIDS

HIV/AIDS Transmission - HIV-1 acquisition may be increased by vaginal washing practice in African women

HIV/AIDS Transmission - Nevirapine dose timing is important to insure adequate serum concentration in infants

HIV/AIDS Transmission - Sexual HIV transmission may bridge high-risk populations with general populations

HIV/AIDS Treatment - HIV management complex in elderly due to drug interactions from comorbid conditions

HIV/AIDS Treatment & Prevention - United Nations supports and strengthens the response to AIDS in China

HIV/AIDS Vaccine - Antibody responses elicited by HIV glycoproteins are characterized

HIV/AIDS Vaccine - HIV therapeutic vaccination is focus of review

HIV/AIDS Vaccine - International AIDS Vaccine Initiative brings new science and technology to the poor

HIV/AIDS Vaccines - Recent findings illuminate research in HIV/AIDS vaccines

HIV/AIDS Vaccines - Recent studies add new data to HIV/AIDS vaccines research

HIV/AIDS Vaccines - Researchers describe findings in HIV/AIDS vaccines studies

HIV/AIDS Vaccines - Researchers report details of new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS-Related CNS Lymphoma - Ganciclovir related to low or undetectable EBV DNA in CSF of AIDS-related CNS lymphoma

HIV/AIDS-Related Immune Reconstitution Syndrome - Immune reconstitution syndrome common in children receiving HAART during advanced AIDS

HIV/AIDS-Related Infection - Delayed development of CMV viremia and HIV/AIDS death associated with positive ELISPOT

HIV/AIDS-Related Lymphoma - Systemic and CNS HIV-related non-Hodgkin lymphoma incidence decreased in HAART era

HIV/AIDS-Related Meningitis - Cranial CT findings differ between HIV-infected and uninfected children with meningitis

HIV/Tuberculosis Coinfection - Coinfection with HIV impacts histopathological features of pericardial TB

Hepatitis A Virus - CD4 count and gender predicts response to HAV vaccine in HIV-positive patients

Hepatitis C Virus - Hepatitis C virus RNA is detected in purified sperm fraction in HIV co-infected patients

Infectious Diseases - Despite flu concerns, HIV, hepatitis most important viral infections to drug developers

Information Technology - International AIDS vaccine R&D program selects enterprise timekeeping software

Kaposi Sarcoma-Associated Herpesvirus - KSHV LANA induces chromosomal instability through inhibition of p53 function

Mergers & Acquisitions - MedMira completes acquisition of SensorChem

Morbidity & Mortality - Health and demographic surveillance conducted in rural western Kenya

Patents - Patent awarded to Enzo for phosphate labeling for DNA diagnostic, medical research items

Personnel - CytoDyn board restructured for anticipated growth; Allen D. Allen re-elected chair

Philanthropy - Pfizer announces new class of global health fellows

Pneumocystis Carinii Pneumonia - Complement and Fc function required for optimal antibody prophylaxis against PCP

Product Licensing - MNLpharma announces license agreement with Avexa to develop compounds to treat HIV/AIDS

SIV Pathogenesis - Cell cycle dysregulation during pathogenic SIV infection correlates with immune activation

Sexual & Reproductive Health - Sexual abstinence among adult woman is associated with positive health behaviors

Virology - Feline immunodeficiency virus restriction by Ref1, Lv1, and TRIM5 alpha proteins is examined

Virology - New research in the area of virology detailed

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