HIV/AIDS Pharmacokinetics
Interpatient variability in plasma efavirenz levels determined by gender and race
Published in AIDS Weekly, March 20th, 2006
In a recently published article, scientists in the Netherlands conducted a study to "characterize the demographic and pharmacogenetic factors that influence interpatient variability in the plasma concentrations of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz. Data from all samples analyzed for efavirenz in our TDM service in 2002 and 2003 were reviewed."
"Information on gender, age, body weight, height, race, hormonal contraceptive use (in a subset of patients), and time between sampling and last intake was recorded.
"PCR-restriction...
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Source: AIDS Weekly (2006-03-20)
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