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HIV/AIDS Therapy

Infants with HIV-1 benefit from early combined antiretroviral therapy

Published in AIDS Weekly, March 27th, 2006

Infants with perinatal HIV-1 infection benefit from early combined antiretroviral therapy.

Researchers in Italy conducted a study "to investigate the impact of early versus deferred combined antiretroviral treatment (ART) in asymptomatic or moderately symptomatic [Centers for Disease Control and Prevention (CDC) category N, A, or B] infants with perinatal HIV-1 infection."

Elena Chiappini at the University of Florence and collaborators explained, "A multicenter nationwide case-control study was conducted. Data from 30 infants treated with combined ART with three or more drugs before six months of age were compared with data from 103 infants starting...

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