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HIV/AIDS Seroreversion

HIV antibody seroreversion does not indicate viral eradication

Published in AIDS Weekly, April 3rd, 2006

HIV antibody seroreversion does not indicate viral eradication.

"We assessed human immunodeficiency virus (HIV) antibody seroreversion among individuals initiating antiretroviral therapy (ART) during acute/early HIV infection and determined whether seroreversion was associated with loss of cytotoxic T lymphocyte responses.

"Subjects in a cohort with acute/early HIV infection ({{<=}}12 months into infection) who initiated ART within 28 days after study entry and maintained HIV type 1 ribonucleic acid levels of {{<=}}500 copies/mL for 124 weeks were selected," scientists writing in the journal Clinical Infectious Diseases report.

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