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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . April 10th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Breast Feeding - HIV-infected mothers do not use formula milk because of social stigma and lack of resources

HIV/AIDS Diagnostics - Discordance between interpretation algorithms for HIV genotypes is subtype dependent

HIV/AIDS Diagnostics - HIV viral load assays compared

HIV/AIDS Evolution - HIV-1 env evolves toward ancestral states upon transmission to a new host

HIV/AIDS Pathogenesis - HIV fusion to dendritic cells declines as cells mature

Aspergillosis Diagnostics - Invasive aspergillosis and mucormycosis rapidly detected by seminested PCR

Business & Finance - Enzo Biochem reports second quarter results, HIV-1 Stealth Vector trial initiated

Clinical Trials - Samaritan starts second phase 2 monotherapy trial of oral anti-viral agent in HIV patients

Contraceptive Microbicide - HIV infection and fertilization targets exploited for contraceptive microbicide development

Depression - Lamivudine and ribavirin regulate serotonin transporter expression

Diagnostics - Medical Services to deliver Dengue Fever rapid test kits to Middle East

Disease Associations - HIV morbidity and mortality is increased in hepatitis C virus co-infection

Disease Associations - HIV/HCV co-infection follow-up is aided by the use of core antigen-based testing

Disease Associations - Lung cancer prognosis is worse in HIV/AIDS than in general population

Drug Development - AnorMED reports AMD070 is active in HIV patients

Drug Development - Immtech completes U.S. FDA special protocol assessment

Finance - Dynavax reports fourth-quarter and year-end results close to previous year

Finance - Progenics Pharmaceuticals reports fourth quarter revenues were $2 million

HIV Transmission - Alkyl sulfate microbicides can be used to treat milk from HIV-1-positive women

HIV/AIDS Dementia - HIV-1 Tat and methamphetamine synergistically destroy dopaminergic terminals in striatum

HIV/AIDS Diagnostics - HIV-1 replication capacity is measured by sensitive FACS-based method

HIV/AIDS Diagnostics - IFN-gamma alone may be insufficient to evaluate breadth of HIV-specific T cell response

HIV/AIDS Diagnostics - Researchers publish new studies and findings in the area of HIV/AIDS diagnostics

HIV/AIDS Drug Adherence - Adherence and response to HAART interaction requires multidisciplinary approach

HIV/AIDS Drug Adherence - HAART adherence improved in Mozambique with free drugs and laboratory testing

HIV/AIDS Drug Development - HIV-1 replication is inhibited in latently infected cells by I kappa B kinase inhibitor

HIV/AIDS Drug Monitoring - Antiretroviral drugs simultaneously detected in plasma by HPLC

HIV/AIDS Epidemiology - HIV drug resistance markers are epidemiologic sentinels for devising public health solutions

HIV/AIDS HAART - HAART needed by 6.5 million people in low- and middle-income countries by end of 2004

HIV/AIDS Microbicide - Preclinical nonoxynol-9 toxicity levels are standardized for HIV microbicide testing protocols

HIV/AIDS Pathogenesis - Basic residues in gag nucleocapsid domain required for HIV-1 Gag-ABCE1 interaction

HIV/AIDS Pathogenesis - HIV integrase-E2C fusion protein strategy achieves site-specific integration

HIV/AIDS Pathogenesis - HIV-1-inducible short hairpin RNA and protein coexpression directed by pol II fusion promoter

HIV/AIDS Prevention - HIV transmission misunderstood by female intravenous drug users in Taiwan

HIV/AIDS Prevention - Mother-adolescent HIV prevention program increases condom use and improves communication

HIV/AIDS Prevention - Studies add new findings to HIV/AIDS prevention body of knowledge

HIV/AIDS Prognostics - Transformed variable Hsp70/CD4+ is less variable than Hsp70 for HIV prognosis

HIV/AIDS Research - U.S. NIH to initiate testing of Mymetics' HIV-AIDS mucosal prophylactic vaccine candidate

HIV/AIDS Therapy - Antiretrovirals not a magic bullet in reducing HIV infection rates; education still essential

HIV/AIDS Therapy - CD4 count at end of HAART interruption influences duration of first interruption

HIV/AIDS Therapy - Enfuvirtide therapy long-term outcome in HIV/AIDS is predicted by week-12 response

HIV/AIDS Therapy - HAART initiation after severe immunosuppression does not restore CD4+ counts in children

HIV/AIDS Therapy - HAART may reduce incidence of AIDS-related events in late-stage infection

HIV/AIDS Therapy - HAART protects against initial and subsequent AIDS-defining illnesses

HIV/AIDS Therapy - NRTI SPD754 is active against group M HIV-1 clades and has low myelotoxicity potential

HIV/AIDS Therapy - Research add new data to HIV/AIDS therapy body of knowledge

HIV/AIDS Therapy - Researchers' work adds to HIV/AIDS therapy body of knowledge

HIV/AIDS Vaccine - Fusion molecules could be the key to producing vaccines from plants

HIV/AIDS Vaccine - Juvaris receives SBIR Advanced Technology NIH-funded grant for HIV vaccine development

HIV/AIDS Vaccine - Multiple epitope-specific CTL responses control immunodeficiency virus replication

HIV/AIDS Vaccine - Novavax receives additional government funding for HIV/AIDS vaccine research

HIV/AIDS Vaccine - Peptide epitope of neutralizing HIV-1 antibody 4E10 analyzed

HIV/AIDS Wasting - Weight loss and wasting remain important AIDS-defining conditions

HIV/AIDS-Associated Lipoatrophy - Lipoatrophy improvement in lower extremities is associated with long-term stavudine withdrawal

HIV/AIDS-Related Depression - Factors associated with depression among homeless HIV-infected men identified

HIV/AIDS-Related Social Impact - HIV disease related to unemployment in France

HIV/Tuberculosis Screening - Chronic cough clinics for suspected TB are used to screen patients for HIV infection

Hepatitis C Virus - Hepatitis C immunopathogenesis is influenced by HIV co-infection

Hepatitis C Virus - Hepatitis C virus treatment efficacy can be predicted

Hepatitis C Virus - Intrahepatic hepatitis C virus replication correlates with disease severity

Human Herpesvirus - Human herpes virus type 8 seroprevalence rate is intermediate-high and stable in Northern Sweden

Malaria Drug Development - Antimalarial activity is seen in HIV protease inhibitors

Occupational Exposure - Compliance inadequate for prevention of occupational exposure to blood and body fluids

Outbreak Surveillance - Surveillance networks linked by Global Outbreak Alert and Response Network

Respiratory Syncytial Virus - RSV genetic variation characterized from consecutive acute respiratory infection isolates

Tuberculosis Drug Resistance - Multidrug-resistant tuberculosis and rifampin resistance prevalence high in Bujumbura

Tuberculosis Drug Resistance - Multidrug-resistant tuberculosis risk factors in Europe determined

Tuberculosis Epidemiology - Multidrug-resistant tuberculosis prevalence is high in Ho Chi Minh City

Tuberculosis Therapy - Tuberculosis therapy compliance improved by directly observed treatment

Vector Development - Recent findings in vector development provide new insights

Virology - Researchers report details of new studies and findings in the area of virology

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