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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . April 17th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Drug Development - HIV-1 replication inhibited with small soluble Tat peptides

HIV/AIDS Pathogenesis - HIV-1 gag destabilizes gp120 and gp4l interaction

HIV/AIDS Pathogenesis - HIV-1 tropism switch from CCR5-to-CXR4 driven by naive and memory cell turnover

HIV/AIDS Vertical Transmission - CCR5 gene polymorphisms related to vertical HIV transmission risk

Hepatitis C & HIV Coinfection - Hepatitis C virus coinfection is associated with decreased adherence to antiretroviral therapy

Atherosclerosis - Atherosclerosis development is associated with antiretroviral HIV therapy

Awards - VH1 receives Joel A. Berger Award for AIDS awareness campaign

Behavioral Medicine - New research in the area of behavioral medicine detailed

Chronic Disease Symptoms - Eleven common symptoms widely spread among five progressive chronic diseases

Chronic Viral Infection - In chronic viral infection, blocking antibodies restore function in exhausted CD8 cells

Clinical Trials - First patients complete infusions in phase II clinical trial for HIV/AIDS gene-based immunotherapy

Diagnostics - MedMira receives Middle East order for 10,000 MiraWell Rapid HIV Tests

Diagnostics - Viral infections diagnosed with noninvasive near-infrared spectroscopy

Drug Development - Anormed reports AMD070 is active in HIV patients

Drug Development - Intranasal IFN gamma extends passive IgA antibody protection against MTB lung infection

Finance - GenVec announces $13.8 million net loss for 2005

Finance - Medical Services sells 290,000 VScan test kits at an average price of US$2.30 in early 2006

Finance - Novavax HIV/AIDS vaccine research program receives $1 million in additional government funding

Finance - Pure Bioscience reports revenues of $59,442 for the second quarter

Finance - Quintiles Transnational Corp. announces $100,000 donation to Seattle Vaccine Research Fund

HIV & Epstein-Barr Virus - Epstein-Barr virus infection dynamics are affected by IL-2 therapy in HIV-coinfected patients

HIV & Kaposi Sarcoma - Kaposi sarcoma incidence has decreased in HIV/AIDS with advent of antiretroviral therapy

HIV/AIDS Behavioral Medicine - Researchers detail new studies and findings in the area of HIV/AIDS behavioral medicine

HIV/AIDS Diagnostics - Low HIV viral loads quantitate higher from blood drawn in plasma preparation tubes

HIV/AIDS Drug Development - Fenretinide inhibits HIV infection by promoting viral endocytosis

HIV/AIDS Drug Development - Researchers provide details of new studies and findings in the area of HIV/AIDS drug development

HIV/AIDS Evolution - HIV-1 recombination may be critical to adaptive viral evolution

HIV/AIDS Exposure - Suppressed cellular alloimmune response may protect against HIV/AIDS in female sex workers

HIV/AIDS HAART - RT levels in HIV-1 particles affect susceptibility to NNRTIs but not to lamivudine

HIV/AIDS HAART - Recent studies add new data to HIV/AIDS HAART research

HIV/AIDS HAART - Reports add new data to HIV/AIDS HAART research

HIV/AIDS Microbicides - Topical vaginal microbicides require vigorous testing for safety and efficacy

HIV/AIDS Pathogenesis - Findings advance knowledge in HIV/AIDS pathogenesis research

HIV/AIDS Pathogenesis - HIV-1 Nef suppresses CD40-dependent Ig class switching in bystander B cells

HIV/AIDS Pathogenesis - HIV-1 infection is inhibited by norepinephrine through NF-kappa B inactivation

HIV/AIDS Pathogenesis - HIV-1 particles bear nonfunctional gp120/gp41 monomers and gp120-depleted gp41 stumps

HIV/AIDS Pathogenesis - IL-7R alpha expression inversely correlates with immune activation in HIV/AIDS

HIV/AIDS Pathogenesis - Immature/transitional B cell population is overly represented in advanced AIDS

HIV/AIDS Pathogenesis - Reports advance knowledge in HIV/AIDS pathogenesis research

HIV/AIDS Pathogenesis - Structurally similar but distinct HIV Vpr/Vpx proteins detrimental to target cells

HIV/AIDS Pathogenesis - TRIM5 alpha gene polymorphisms not associated with HIV-1 susceptibility of CD4+ cells

HIV/AIDS Prognostics - Low adiponectin levels predict VLDL and IDL apolipoprotein B fractional clearance rates

HIV/AIDS Psychosis - Antisocial personality disorder blunts HAART effects on event-related brain potentials

HIV/AIDS Risk Factors - HIV sexual and injection-risk behavior vary by recruitment site in Philadelphia

HIV/AIDS Risk Reduction - Mothers are effective as HIV risk reduction educators for adolescent daughters

HIV/AIDS Therapy - Buprenorphine therapy in primary HIV care setting improves therapeutic adherence

HIV/AIDS Therapy - Failure of HIV-exposed T cells to activate dendritic cells is reversible

HIV/AIDS Therapy - Kenya healthcare survey shows progress in treating AIDS but battle for services continues

HIV/AIDS Transmission - HIV prevention through universal maternal/neonatal vitamin A dosing may not be beneficial

HIV/AIDS Transmission - Researchers' data advance HIV/AIDS transmission research

HIV/AIDS Vaccine - HIV-1 subtype C vaccines focus on proteins derived from HIV-1C

HIV/AIDS Vaccine - Immunized HIV-1-infected individuals displayed sustained control of viremia

HIV/AIDS Vaccine Development - HIV serodetection assay differentiates vaccine- from virus-induced antibodies

HIV/AIDS Vaccine Development - RANTES expressed from chimeric SHIV-RANTES suppresses CCR5-tropic HIV-1 replication

HIV/AIDS Vaccines - New findings in HIV/AIDS vaccines described

HIV/AIDS Vaccines - New findings in the area of HIV/AIDS vaccines detailed

HIV/AIDS Vaccines - Reports describe recent advances in HIV/AIDS vaccines research

HIV/AIDS Vaccines - Studies describe new findings in HIV/AIDS vaccines research

HIV/AIDS Viral Fitness - HIV-1 replication fitness estimated in growth competition assay

HIV/AIDS-Associated Cryptosporidiosis - Cryptosporidial diarrhea associated with decreased CD4 counts but not high HIV RNA

HIV/AIDS-Related Cat-Scratch Disease - Fluorescein angiography detects ocular manifestation of cat-scratch disease in HIV/AIDS

Hepatitis B Virus - Hepatitis B surface and core antigen coinoculation promotes HIV-1 immune response

Infectious Diseases - AIDS, TB, malaria, and avian influenza spreading unchecked in Burma

Kaposi Sarcoma-Associated Herpesvirus - KSHV IFN regulatory factor 1 inhibits ATM/p53 signal transduction pathway

Liver Fibrosis & HIV - Hepatitis B genotypes participate in liver fibrosis during coinfection with HIV

Liver Injury - Liver injury in HIV-infected patients can be associated with altered hepatic expression

Market Analysis - IMS Health reports global pharmaceutical market grew 7% in 2005, to $602 billion

Nucleic Acid Preservation - Lyophilized viral DNA and RNA stable even after prolonged storage

Patents - Efoora announces provisional patent filing for VCT+

Patents - MedMira files patent for infectious disease over-the-counter testing system

Plastic Surgery - Hip and buttock implants enhance feminine contours for HIV/AIDS patients

Pneumococcal Vaccine - C-reactive protein assesses pneumococcal conjugate vaccine efficacy in preventing pneumonia

Pneumocystis Carinii Pneumonia -  Pneumocystis carinii pneumonia occurs in immunosuppressive disease and therapies

Prison Health - Inadequate medical information systems impede TB control and evaluation efforts in jails

Tuberculosis - New York researchers' development may lead to new drugs for tuberculosis

Tuberculosis Therapy - Linezolid active against multidrug-resistant tuberculosis but may cause peripheral neuropathy

Tuberculosis Vaccines - Studies describe new findings in tuberculosis vaccines research

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