Published in AIDS Weekly, April 17th, 2006
According to recent research published in the journal Nature, "Functional impairment of antigen-specific T cells is a defining characteristic of many chronic infections, but the underlying mechanisms of T-cell dysfunction are not well understood."
"To address this question, we analyzed genes expressed in functionally impaired virus-specific CD8 T cells present in mice chronically infected with lymphocytic choriomeningitis virus (LCMV), and compared these with the gene profile of functional memory CD8 T cells," wrote .L. Barber and colleagues at Emory...
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