HIV/AIDS Transmission
HIV-1 susceptibility may be influenced by DC-SIGN-related molecule polymorphisms
Published in AIDS Weekly, April 24th, 2006
According to a study from the United States, "In 1716 individuals (801 human immunodeficiency virus (HIV)-1-seropositive individuals, 217 high-risk HIV-1-seronegative individuals, and 698 general HIV-1-seronegative individuals) from a Seattle cohort and a Multicenter AIDS Cohort Study cohort, the association between HIV-1 susceptibility and repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule (DC-SIGNR) was investigated."
"Sixteen genotypes were found in the DC-SIGNR repeat region....
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Source: AIDS Weekly (2006-04-24)
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