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Herpes

Studies from the United States and Austria describe new findings in herpes research

Published in AIDS Weekly, May 1st, 2006

Investigators in the United States and Austria have published new herpes data.

Study 1: Focal adhesion kinase is critical for Kaposi's sarcoma-associated herpesvirus cell entry.

"Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSRV/HHV-8) interacts with cell surface alpha 3 beta 1 integrin early during in vitro infection of human endothelial cells and fibroblasts and activates the focal adhesion kinase (FAK) that is immediately downstream in the outside-in signaling pathway by integrins, leading to the activation of several downstream signaling molecules.

"In this study, using real-time DNA and reverse...

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