Published in AIDS Weekly, May 1st, 2006
Study 1: Focal adhesion kinase is critical for Kaposi's sarcoma-associated herpesvirus cell entry.
"Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSRV/HHV-8) interacts with cell surface alpha 3 beta 1 integrin early during in vitro infection of human endothelial cells and fibroblasts and activates the focal adhesion kinase (FAK) that is immediately downstream in the outside-in signaling pathway by integrins, leading to the activation of several downstream signaling molecules.
"In this study, using real-time DNA and reverse...
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