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Adverse Drug Reaction

Adverse drug reactions to antiretroviral drugs are influenced by hepatitis virus

Published in AIDS Weekly, May 1st, 2006

In a recently published study, investigators in France reported that adverse drug reactions (ADRs) to antiretroviral (ARV) drugs are influenced by hepatitis viruses.

E. Guitton and colleagues, Laboratoire de Pharmacologie Médicale et Clinique, wrote that the study was done "to compare the profile of ADRs to ARV drugs in patients coinfected with hepatitis C virus (HCV) or hepatitis B virus (HBV) versus non-coinfected patients with human immunodeficiency virus (HIV) infection."

"We used the French Pharmacovigilance Database from 2000 to 2002. Selected patients were classified into four groups: HIV+HCV, HIV+HBV, HIV+HBV+HCV and HIV patients. We compared...

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