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HIV/AIDS Research

T cell subpopulations change during 4 years of suppression of HIV-1 replication

Published in AIDS Weekly, May 1st, 2006

University T-cell subpopulations change during 4 years of suppression of HIV-1 replication in patients with advanced disease.

According to recent research from Croatia, "We compared the number/percentages of naive and memory CD4(+) T-cells, CD38(+)CD8(+) T-cells, and CD28(+)CD4(+) and CD28(+)CD8(+) T-cells in patients with advanced HIV disease (baseline CD4(+) count <100) with those with less advanced (baseline CD4(+) cell count >100) HIV disease during 4 years of suppressive highly active antiretroviral therapy. This prospective, longitudinal study included 30 treatment-naive patients and 32 controls."

"Advanced HIV-infected patients (n=13)...

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