HIV/AIDS Vaccine
Anti-dendritic cell HIV gag fusion antibody vaccine intensified CD4+ T cell immunity
Published in AIDS Weekly, May 29th, 2006
According to researchers in the United States, "Current human immunodeficiency virus (HIV) vaccine approaches emphasize prime boost strategies comprising multiple doses of DNA vaccine and recombinant viral vectors. We are developing a protein-based approach that directly harnesses principles for generating T cell immunity."
"Vaccine is delivered to maturing dendritic cells in lymphoid tissue by engineering protein antigen into an antibody to DEC-205, a receptor for antigen presentation. [In our report] we characterize the CD4+ T cell...
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Source: AIDS Weekly (2006-05-29)
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