HIV/AIDS
Data from Italy, Spain and the United States advance knowledge in HIV/AIDS research
Published in AIDS Weekly, June 5th, 2006
Study 1: Amino acid insertions at position 35 of HIV-1 protease interfere with virus replication without modifying antiviral drug susceptibility.
According to a study from Italy, "Among 1,330 patients undergoing highly active antiretroviral therapy (HAART), three showed one or two amino acid (aa) insertions at position 35 of the HIV-1 protease gene. Protease genes containing aa insertions, either in the presence (ins35G+res.muts, ins35TN+res.muts) or absence (ins35G, ins35TN) of other resistance mutations, were introduced into the wild-type HIV-1 strain NL4-3. The...
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Source: AIDS Weekly (2006-06-05)
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