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Pfizer and Monogram to make HIV coreceptor tropism assay available globally

Published in AIDS Weekly, June 5th, 2006

Pfizer Inc (PFE) and Monogram Biosciences, Inc. (MGRM) announced a non-exclusive collaboration to make Monogram's HIV coreceptor tropism assay available for patient use on a global basis.

The assay is a diagnostic tool to show tropism - the path taken by the virus to access human CD4 cells.

Tropism information is intended to help identify patients who are most likely to respond to a class of investigational drugs known as CCR5 antagonists. CCR5 antagonists are designed to block viral cell entry through the CCR5 coreceptor. Studies have shown that 80-85% of people newly diagnosed with HIV and previously untreated with HIV therapy have dominant...

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