HIV/AIDS Transmission
Vaginal epithelial cells implicated in heterosexual HIV transmission
Published in AIDS Weekly, June 12th, 2006
According to a study from France, "Heterosexual human immunodeficiency virus (HIV) transmission implies the crossing of the vaginal mucosa by virions present in the semen, potentially using Langerhans cells as transporters. The recruitment of these cells in the mucosa is mediated by the chemokine macrophage inflammatory protein 3 alpha (CCL20)."
"The aim of this study was to evaluate the capacity of the semen to induce Langerhans cell recruitment via the production of CCL20 by vaginal epithelial cells," said W. Berlier and colleagues at Groupe Immunite des Muqueuses et Agents...
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Source: AIDS Weekly (2006-06-12)
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