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Genetics

Researchers from the United Kingdom and United States describe findings in genetics studies

Published in AIDS Weekly, June 19th, 2006

Genetics research advances have been reported from the United Kingdom and United States.

Study 1: According to a study from England, gene silencing of HIV chemokine receptors is achieved using ribozymes and single-stranded antisense RNA.

"The chemokine receptors CXCR4 and CCR5 are required for HIV-1 to enter cells, and the progression of HIV-1 infection to AIDS involves a switch in the co-receptor usage of the virus from CCR5 to CXCR4. These receptors therefore make attractive candidates for therapeutic intervention, and we have investigated the silencing of their genes by using ribozymes and single-stranded antisense RNAs," wrote A. Qureshi and...

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