AIDS Weekly

HIV/AIDS HAART - HIV/AIDS patients on efavirenz therapy have high-density lipoprotein cholesterol increase

HIV/AIDS Screening - Risk-based HIV testing does not detect majority of infected persons in healthcare settings

HIV/AIDS Transmission - Simian HIV spreads quickly to systemic tissues after mucosal transmission

HIV/AIDS Vertical Transmission - Perinatal HIV transmission may be prevented by neutralizing antibodies

HIV/Leishmania Coinfection - HIV-1 indirectly affects uptake of Leishmania inside monocyte-derived macrophages

Business Update - Medical Services reports documentation complete for CE approval on HIV test kit in Europe

Candidiasis - Montreal researchers identify defective immune cells that determine susceptibility to candidiasis

Drug Development - Boehringer Ingelheim provides update on Aptivus trial in treatment-naive HIV-infected patients

Epidemiology - HIV-1 R5 variants from X4 phenotypes are under weakly positive selective pressures

Finance - Immune Response Corporation announces $4.1 million received in private placement financing

HIV/AIDS & Pregnancy - Impact of HIV infection during pregnancy on maternal and fetal outcomes was evaluated

HIV/AIDS & Tuberculosis - Nearly half of new TB cases are acquired from HIV-infected household contacts in Malawi

HIV/AIDS Genetics & Genomics - Nepal macaques genetically resemble Indian macaques more than those of Chinese origin

HIV/AIDS Pathogenesis - HIV-1 and murine leukemia virus protease are only distantly related in their specificity

HIV/AIDS Pathogenesis - RNA helicase A associates with HIV-1 Gag in an RNA-dependent manner

HIV/AIDS Prevention - Abstinence messages are not enough for HIV prevention in Zambia

HIV/AIDS Prevention - Syringe-exchange programs prevent HIV transmission yet remain controversial

HIV/AIDS Research - CHAVI announces international search for genes affecting HIV response

HIV/AIDS Therapy - HIV-1 antiviral activity exhibited following delivery of double-stranded DNA

HIV/AIDS Therapy - HIV-1 cytokine profiles are affected by HAART and HCV co-infection

HIV/AIDS Therapy - Phase 3 trial to be initiated in Europe to speed development of HIV oral entry inhibitor

HIV/AIDS Vaccine - Anti-V3 humanized antibody KD-247 protects monkeys against SHIV infection

HIV/AIDS Vaccine - V3 peptides from HIV-1 produce cross-neutralizing antibodies against primary isolates

Hepatitis C Therapy - Hepatitis C rate of infectious complications is not related to neutropenia

Kaposi Sarcoma-Associated Herpesvirus - Kaposi sarcoma-associated herpesvirus latency reactivation triggered by Raf/MEK/ERK signaling

Patents - MatTek's EpiVaginal receives U.S. patent for HIV/AIDS research

Pneumocystis Drug Development - PCA1 inhibitors screened for identification of anti-Pneumocystis agents

Pneumonia Therapy - Death from pneumococcal pneumonia not associated with initial antibiotic choice

Vaccine Development - DNA plasmid vaccines display similar biodistribution

Vector Development - Recombinant SV40 vectors transduce microglia and protect against HIV

Virus Replication - Virus replication sites generated by aggresomes and autophagy

Genetics - Research from the United States, Spain and Iceland add new data to genetics body of knowledge

HIV/AIDS - Data from Germany, the United States and Sweden advance knowledge in HIV/AIDS research