Published in AIDS Weekly, July 10th, 2006
Study 1: Cells knocked-out for Lens epithelium-derived growth factor (LEDGF)/p75 and/or hepatoma-derived growth factor related protein 2 (HRP2) will be useful genetic tools to address the roles of these host cell factors in human immunodeficiency virus type 1 (HIV-1) replication.
According to recent research published in the journal Virology, "Human immunodeficiency virus type 1 integrase (IN) functions in cells within the context of high molecular weight preintegration complexes (PICs). Lens epithelium-derived growth factor (LEDGF) transcriptional coactivator/p75 and...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2006-07-10)
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.