AIDS Weekly

AIDS/Tuberculosis Coinfection -  Schistosoma mansoni is associated with progression to active tuberculosis in HIV/AIDS

HIV/AIDS Antiviral - Apolipoprotein B editing catalytic polypeptidedeaminases act as cellular antiviral factors

HIV/AIDS Drug Resistance - HIV-1 K65R mutation may emerge preferentially in absence of zidovudine and TAMs

HIV/AIDS HAART - Reduced adherence only partly explains differences in viral suppression from HAART regimens

HIV/AIDS Phenotyping - HIV envelope V3 sequences predicts phenotype for HIV-1 subtype C

Adverse Drug Reaction - Severe liver disease is associated with prolonged antiretroviral drug exposure

Blood Safety - Safe Blood Foundation, Chinese Ministry of Health partner to develop blood quality manual

Business Update - Bangalore, India-based Strides Arcolab receives fifth HIV product approval from WHO

Business Update - Medical Services International to ship VScan HIV test kits into several European countries

DNA Research - Cytidine deamidase biochemical activities correlate with antiviral effect

Diagnostics - 3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of HIV

Drug Delivery - pSivida files U.K. patent application for drug delivery platform that can act as adjuvant

Finance - Chembio closes bridge financing

HIV-1 Integrase - Screening program identifies 11 small-molecule inhibitors of HIV-1 integrase

HIV/AIDS & Burkitt Lymphoma - HIV-associated Burkitt lymphoma successfully treated with chemotherapy plus HAART

HIV/AIDS & Kaposi Sarcoma - Survival remains poor for HIV/AIDS patients with pulmonary Kaposi sarcoma

HIV/AIDS Cardiology - Atazanavir does not result in increases in cardiac corrected QT interval or QT dispersion

HIV/AIDS Cardiology - Right ventricular volume dysfunction not a major clinical problem in HAART-treated patients

HIV/AIDS Caregiving - Stigma associated with AIDS patient caregivers leads to social isolation

HIV/AIDS Diet & Nutrition - HIV infection does not influence vitamin D status

HIV/AIDS Diet & Nutrition - Polyunsaturated fatty acid intake adversely related to liver function in HIV/AIDS

HIV/AIDS Disclosure - Parents often do not disclose their HIV status to their children

HIV/AIDS Drug Adherence - 'Simply forgot' is most frequently stated reason for missed doses of HAART

HIV/AIDS Drug Development - Oral CCR5 inhibitors are under development for treatment of HIV-1 infection

HIV/AIDS Drug Resistance - HIV-1 variants at increasing capravirine levels contain multiple substitutions in diverse patterns

HIV/AIDS Epidemiology - Predictive demographic factors for HIV positivity determined for Thai clinic attendees

HIV/AIDS Mental Health - Psychiatric disorders prevalent in youth with perinatally-acquired HIV infection

HIV/AIDS Pathogenesis - Cyclophilin A alters HIV-1 sensitivity to a TRIM5 alpha-independent innate immune pathway

HIV/AIDS Pathogenesis - HIV-1 infectivity regulated by inner-nuclear-envelope protein emerin

HIV/AIDS Pathogenesis - HIV-1 RNA encapsulation occurs mainly in trans

HIV/AIDS Pathogenesis - HIV-1 Tat is a potent pathological agonist at metabotropic glutamate receptor 1 receptors

HIV/AIDS Pathogenesis - Stimulated mRNA expression in activated T cells depends on functional CRM1 nuclear export pathway

HIV/AIDS Prevention - Randomized trials needed to determine whether adult male circumcision reduces HIV risk

HIV/AIDS Research - Women who transmit HIV to their offspring were less likely to have autologous neutralizing antibody

HIV/AIDS Risk Factors - HIV transmission risk by oral sex is low due to several possible factors

HIV/AIDS Testing - OraSure Technologies signs purchase contract for OraQuick Advance Rapid HIV-1/2 antibody tests

HIV/AIDS Therapy - Abbott's new tablet form of Kaletra (lopinavir/ritonavir) is approved in Europe

HIV/AIDS Therapy - HIV-infected women show improvement in physical fitness measures through exercise program

HIV/AIDS Therapy - Prezista receives U.S. FDA approval as part of HIV combination therapy

HIV/AIDS Therapy - Response rates to combination anti-HIV therapy are improving across Europe

HIV/AIDS Therapy - Risk factors for follow-up interruption of HIV/AIDS treatment identified in French Guiana

HIV/AIDS Vaccine - Lentiviral vectors expressing HIV-1 Rev/Env or HIV-1gp120 generate durable immune responses

HIV/AIDS Vaccine - Vaccine-induced immune responses reduce SIVmac239 concentrations