Published in AIDS Weekly, August 21st, 2006
According to a report recently published in Protein Expression and Purification, "Trimeric HIV-1 envelope glycoproteins (Env) are now being evaluated instead of monomeric gp120 as vaccine antigens because they mimic more closely the spikes expressed on the surface of virions. Thus, it can be argued that trimers have a more native structure than gp120, so might be superior at raising neutralizing antibodies."
"One approach to making Env...
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