HIV/AIDS Perinatal Transmission
Maternal autologous neutralizing antibody protective against perinatal HIV-1 transmission
Published in AIDS Weekly, August 21st, 2006
"Perinatal human immunodeficiency virus type 1 (HIV-1) transmission is characterized by acquisition of a homogeneous viral quasispecies, yet the selective factors responsible for this genetic bottleneck are unclear.
"We examined the role of maternal autologous neutralizing antibody (aNAB) in selective transmission of HIV-1 escape variants to infants," wrote investigators in the United States.
According to R. Dickover and colleagues at the University of California, Los Angeles, "Maternal sera from 38 infected mothers at the time of...
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Source: AIDS Weekly (2006-08-21)
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