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HIV/AIDS

Research from France, the United States and Italy in HIV/AIDS provides new insights

Published in AIDS Weekly, August 28th, 2006

Reports from France, the United States and Italy highlight recent research in HIV/AIDS.

Study 1: Purified anti-HIV-1 IgG without induction of maturation inhibited HIV-1 replication in human immature monocyte-derived dendritic cells.

According to a study from France, "During mucosal HIV transmission, immature dendritic cells (DCs) present in the mucosa are among the first cellular targets of the virus. Previous studies have analyzed the inhibition of HIV-1 transfer from human mature DCs to T lymphocytes by neutralizing IgG, but so far no in vitro data regarding the capacity of antibodies to inhibit HIV-1 infection of immature DCs have been...

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