AIDS Weekly

HIV/AIDS Pathogenesis - Tumor susceptibility gene 101 variability associated with HIV disease progression

HIV/AIDS Therapy - Arginine 332 removal allows human TRIM5 alpha to bind HIV capsids and restrict infection

HIV/AIDS Transmission - Seminal interleukin-1 beta amount positively correlates with HIV-1 load in semen

HIV/AIDS Vertical Transmission - Cure rate model predicts age at which HIV infection can be detected in infants

Hormone Research - Oral dehydroepiandrosterone therapy increases hormone levels in HIV-infected men

Awards - Northwestern receives Gates Foundation grant for medical diagnostics for developing countries

Business & Finance - Idenix Pharmaceuticals reports second-quarter revenues of $19.3 million

Business Update - Medical Services increases distributor network for VScan test kits into Balkan regions

Business Update - StatSure Diagnostic Systems signs deal with Inverness Medical Innovations for rapid HIV test

Business Update - Tanox conducts meeting with U.S. FDA on developing HIV/AIDS antibody TNX-355

Drug Development - Quigley compound QR-443 effective in preventing cachexia

Finance - Tanox reports Q2 2006 revenues of $12.7 million compared to $7.4 million a year ago

Finance - Targeted Genetics reports Q2 2006 revenues of $1.4 million, down from $1.5 million a year ago

Gonorrhea Diagnostics - Localized gonorrhea transmission networks identified by strain characterization method

HIV/AIDS & Leishmaniasis - Visceral leishmaniasis/HIV coinfection increasing in India

HIV/AIDS & Malaria - Cotrimoxazole prophylaxis reduces overall mortality and malaria morbidity in HIV patients

HIV/AIDS & Osteonecrosis - HIV-related osteonecrosis associated with significant disability

HIV/AIDS & Pneumocystis -  Pneumocystis jirovecii dihydropteroate synthase mutations rare in HIV/AIDS patients in Brazil

HIV/AIDS & Spastic Paraparesis - HIV encephalopathy-related spastic paraparesis treated with intrathecal baclofen

HIV/AIDS Awareness - M.A.C. gives lipstick; fashion designers donate red gowns to support AIDS awareness

HIV/AIDS Behavioral Medicine - Depressive symptoms predict sexual risk behavior among teenagers

HIV/AIDS Contact Dermatitis - Allergic contact dermatitis to basic red 46 occurred in HIV/AIDS

HIV/AIDS Diagnostics - Clinical criteria alone identify HIV-infected patients who need HAART

HIV/AIDS Epidemiology - Increased HIV prevalence associated with incarceration among intravenous drug users in Tehran

HIV/AIDS Evolution - Simian immunodeficiency virus SIVcpz evolution and transmission routes explored

HIV/AIDS HAART - HAART adherence associated with lower viral reproductive ratio

HIV/AIDS HAART - HAART adherence improved by home visits

HIV/AIDS HAART - Hypersusceptibility to substrate analogs conferred by HIV-1 reverse transcriptase mutations

HIV/AIDS Knowledge - Sexual activity and HIV/AIDS knowledge explored among teenagers and adults in rural Kenya

HIV/AIDS Mental Health - Prevalence of mood and anxiety disorders and substance abuse determined among HIV patients

HIV/AIDS Pathogenesis - Correlation between CD8 responses and HIV RNA or CD4 count not consistent throughout infection

HIV/AIDS Pathogenesis - HIV-1 inhibited in macrophages following LEDGFp75 silencing

HIV/AIDS Pathogenesis - HIV-1 protease functions best when residue 80 is a small polar residue

HIV/AIDS Pathogenesis - HIV-1 transframe protein p6* mutation needed for viral protease-mediated Gag processing

HIV/AIDS Pathogenesis - Phenotypic recessive, post-entry block in rabbit cells causes aberrant trafficking of HIV-1

HIV/AIDS Pathogenesis - Preferential infection shortens HIV-1-specific CD4+ T cell lifespan

HIV/AIDS Pathogenesis - Splice donor site in HIV gag-pol gene is required for viral RNA stability

HIV/AIDS Postexposure Prophylaxis - HIV postexposure prophylaxis completion rates low among adolescent sexual assault victims

HIV/AIDS Prevention - Required coverage of syringe distribution to prevent HIV infection among IDUs determined

HIV/AIDS Prevention - Scytovirin peptide displays potent anti-HIV activity

HIV/AIDS Prognostics - HIV dynamic model incorporating drug susceptibility and adherence predicts virological response

HIV/AIDS Progression - Genetic factors identified that explain 9% of slow progression to AIDS

HIV/AIDS Progression - Plasma HIV RNA levels differ among HAART-treated children according to gender

HIV/AIDS Research - Dendritic cell therapeutic vaccine helps patient's own immune system to fight HIV infection

HIV/AIDS Research - Panel updates guidelines for treatment of adult HIV infection