HIV/AIDS Pathogenesis
Tumor susceptibility gene 101 variability associated with HIV disease progression
Published in AIDS Weekly, September 4th, 2006
"Tumor susceptibility gene 101 (TSG101) encodes a host cellular protein that is appropriated by human immunodeficiency virus type 1 (HIV-1) in the budding process of viral particles from infected cells.
"Variation in the coding or noncoding regions of the gene could potentially affect the degree of TSG101-mediated release of viral particles," scientists writing in the Journal of Virology report.
According to A.A. Bashirova and colleagues at the U.S. National Institutes of Health, "While the coding regions of the gene were found to lack...
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Source: AIDS Weekly (2006-09-04)
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