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Kaposi Sarcoma

Studies from Japan and the United States add new findings to Kaposi sarcoma body of knowledge

Published in AIDS Weekly, September 18th, 2006

New findings from Japan and the United States describe advances in Kaposi sarcoma.

Study 1: Kaposi sarcoma-associated herpesvirus RTA induces a transcriptional repressor that represses rta promoter.

According to recent research from Japan, "Kaposi's sarcoma-associated herpesvirus (KSHV) is a gamma-herpesvirus that is frequently associated with the formation of tumors like Kaposi's sarcoma and primary effusion lymphomas. KSHV RTA is required for lytic replication/reactivation in KSHV-infected cells."

"We developed an inducible RTA expression cell line to search for RTA-inducible genes. Using DNA chip technology, we showed that HEY1...

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