HIV/AIDS
Researchers' work from Denmark and the United States adds to HIV/AIDS body of knowledge
Published in AIDS Weekly, September 18th, 2006
Study 1: A splice donor site in the HIV gag-pol gene is required for viral RNA stability.
"Productive infection and successful replication of human immunodeficiency virus 1 (HIV-1) requires the balanced expression of all viral genes. This is achieved by a combination of alternative splicing events and regulated nuclear export of viral RNA.
"Because viral splicing is incomplete and intron-containing RNAs must be exported from the nucleus where they are normally retained, it must be ensured that the unspliced HIV-1 RNA is actively exported from the...
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Source: AIDS Weekly (2006-09-18)
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